Activation of Ca-Dependent Currents in Dorsal Root Ganglion Neurons by Metabotropic Glutamate Receptors and Cyclic ADP- Ribose Precursors
نویسندگان
چکیده
JANE H. CRAWFORD, JOHN F. WOOTTON, GUY R. SEABROOK, AND RODERICK H. SCOTT Merck Sharp and Dohme, Neuroscience Research Centre, Harlow, Essex CM20 2QR, United Kingdom; Department of Physiology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853-601; and Department of Biomedical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom
منابع مشابه
Activation of Ca2+-dependent currents in dorsal root ganglion neurons by metabotropic glutamate receptors and cyclic ADP-ribose precursors.
Cultured dorsal root ganglion neurons were voltage clamped at -90 mV to study the effects of intracellular application of nicotinamide adenine dinucleotide (betaNAD+), intracellular flash photolysis of caged 3',5'-cyclic guanosine monophosphate (cGMP), and metabotropic glutamate receptor activation. The activation of metabotropic glutamate receptors evoked inward Ca2+-dependent currents in most...
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